Open AccessPeripheral T-cell lymphoma, not otherwise specified
Author(s) -
Kunal Jha,
Suresh Gupta,
Harpreet Saluja,
Nuwadatta Subedi
Publication year - 2017
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_323_16
Subject(s) - medicine , hypergammaglobulinemia , thrombocytosis , lymphocytosis , lymphoma , eosinophilia , pathology , anemia , biopsy , generalized lymphadenopathy , peripheral t cell lymphoma , rash , t cell lymphoma , disease , immunology , t cell , platelet , immune system
The peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) belongs to a heterogeneous class of aggressive neoplasms. Although several morphologic subtypes of this tumor have been described, no particular genetic, immunological, or distinct clinical features define this disease. Patients can experience night sweats, fever, lymphadenopathy, weight loss, splenomegaly, and/or skin changes. Common laboratory tests reveal that patients have anemia, thrombocytosis, lymphocytosis, eosinophilia, hypergammaglobulinemia, or increased lactate dehydrogenase. In this case study, a patient presented with massive lymphadenopathy and right lower limb swelling, which he developed over 6 weeks. A tissue biopsy and supporting investigations confirmed the diagnosis of PTCL, NOS.