Open AccessObservational study on the response of tenofovir monotherapy versus tenofovir plus telbivudine dual therapy in patients with hepatitis B virus related acute on chronic liver failure
Author(s) -
Abul Hayat Manik,
Debraj Malakar,
Sheikh Mohammad Noor-E-Alam,
Mamun Al-M Mahtab,
Debasish Das,
Ayub Al Mamun,
Md. Sakirul Islam Khan,
Mohammad Fazle Akbar,
Zakiur Rahman,
Salimur Rahman
Publication year - 2021
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_2300_20
Subject(s) - medicine , telbivudine , tenofovir , observational study , chronic hepatitis , entecavir , hepatitis b virus , gastroenterology , virus , virology , lamivudine , human immunodeficiency virus (hiv)
HBV is major health problem globally due to complications, including ACLF, cirrhosis and hepa¬tocellular carcinoma. ACLF due to exacerbation of CHB is associate with 30%-70% mortality. Reduction of HBV-DNA is therefore a target of therapy in ACLF-B.