Open AccessHemophagocytic lymphohistiocytosis as a diagnostic consideration of fever of unknown origin with pancytopenia and chronic liver disease
Author(s) -
Fnu Amisha,
Paras Malik,
Monika Pathania,
Vyas Kumar Rathaur,
Nidhi Kaeley
Publication year - 2019
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_190_19
Subject(s) - pancytopenia , medicine , hemophagocytic lymphohistiocytosis , malignancy , disease , immunology , immune dysregulation , immune system , pathology , bone marrow
Hemophagocytic lymphohistiocytosis (HLH) is a severe disorder of systemic immune dysregulation which can be primary or secondary to autoimmune disorders, malignancy, or infections. We hereby describe a case of a 23-year-old male with severe hepatitis along with pancytopenia and prolonged fever of unknown origin that developed HLH triggered by staphylococcal urinary tract infection. This is a discussion of this unusual disease and its presentation and the diagnostic difficulties which may be encountered in general clinical practice.