Open AccessAn investigation of the effectiveness of oral cyclosporine on perioperative myocardial injury (PMI) in patients who undergo the surgical procedure of coronary artery bypass graft (CABG): A Randomized Controlled Clinical Trial
Author(s) -
Seyed Mohammad Hassan Adel,
Mohammad Ali Sheikhi,
M Dorra
Publication year - 2021
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_1598_20
Subject(s) - medicine , perioperative , troponin i , placebo , myocardial infarction , anesthesia , surgery , diabetes mellitus , cardiology , alternative medicine , pathology , endocrinology
Routine clinical strategies for the prevention of myocardial infarction (MI) during the surgical procedure of CABG include cross-clamp fibrillation and cardioplegia have failed to decrease the risk of perioperative myocardial injury (PMI). Cyclosporine-A (CsA) might be able to prevent mitochondrial dysfunction and PMI.