Open AccessComparison between sperm parameters and chromatin in recurrent pregnancy loss couples after antioxidant therapy
Author(s) -
Alireza Nazari,
Parvin Sabeti,
Soheila Pourmasumi
Publication year - 2020
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_1105_19
Subject(s) - sperm , dna fragmentation , medicine , andrology , antioxidant , vitamin c , vitamin e , pregnancy , chromatin , tunel assay , biology , apoptosis , dna , biochemistry , genetics , immunohistochemistry , programmed cell death
Recurrent Pregnancy loss (RPL) is a heterogeneous disease. The role of maternal factor is clear but the relationship between the paternal factors remains uncertain. It has been shown that increase the level of Reactive Oxygen Species (ROS) and decrease the antioxidant levels in men can lead to RPL. New researches show treatment with antioxidant can improved sperm parameter. The aim of the present study was to assess the effect of vitamin E plus Zinc therapy on sperm parameters and chromatin quality in couples with RPL.