Open AccessManagement of siblings with Glanzmann's thrombasthenia: A case report
Author(s) -
Mebin George Mathew
Publication year - 2020
Publication title -
journal of family medicine and primary care
Language(s) - English
Resource type - Journals
eISSN - 2278-7135
pISSN - 2249-4863
DOI - 10.4103/jfmpc.jfmpc_1083_19
Subject(s) - medicine , glanzmann's thrombasthenia , thrombasthenia , mucocutaneous zone , pediatrics , dermatology , major bleeding , platelet , surgery , disease , platelet aggregation , myocardial infarction
Glanzmann's thrombasthenia is a rare, genetically inherited platelet disorder characterized by a lack of platelet aggregation. Until date, only close to 500 cases have been reported. GT is associated with clinical variability: some patients have only minimal bruising while others have frequent, severe and potentially fatal hemorrhages often making diagnosis difficult. Children are mostly diagnosed very early in life due to the spontaneous and unexplained mucocutaneous bleeding. The present case report deals with two siblings who reported with spontaneous gingival bleeding who were successfully managed by removal of local irritant factors and proper supportive care.