Open AccessComparative study of the efficacy and safety of intranasal azelastine hydrochloride and fluticasone furoate in the treatment of allergic rhinitis
Author(s) -
Nandish Chennakeshavaraju,
N Sarala,
Azeem Mohiyuddin
Publication year - 2020
Publication title -
journal of family and community medicine/maǧalaẗ ṭib al-usraẗ wa al-muǧtamaʼ
Language(s) - English
Resource type - Journals
eISSN - 2229-340X
pISSN - 1319-1683
DOI - 10.4103/jfcm.jfcm_103_20
Subject(s) - medicine , fluticasone propionate , azelastine , rhinorrhea , nasal administration , mometasone furoate , nasal spray , eosinophil , fluticasone , adverse effect , anesthesia , nose , gastroenterology , asthma , corticosteroid , surgery , pharmacology
Allergic rhinitis (AR) is characterized by nasal itch, sneezing, watery or mucous rhinorrhea, nasal obstruction, and nasal or pharyngeal irritation. If untreated, AR can impair patients' quality of life (QOL). Azelastine hydrochloride (AH), histamine receptor antagonists, has anti-inflammatory and mast cell stabilizing properties. Fluticasone furoate (FF) is an anti-inflammatory agent with action on mast cells, eosinophils, neutrophils, macrophages, and lymphocytes. This study compares the efficacy and safety of these medications in AR.