Open AccessComprehensive treatment for multicentric giant cell tumors of the pelvis and spine using apatinib: A case report and literature review
Author(s) -
Jun Li,
Jun Zhou,
Yuntong Liu,
Xiaogang Sun,
Wei Song
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_892_19
Subject(s) - apatinib , medicine , denosumab , zoledronic acid , surgery , sacrum , bisphosphonate , vomiting , pelvis , chemotherapy , osteoporosis
There are no standardized treatments for giant cell tumors of the bone (GCTB) in rare locations such as the spine and pelvis or for those that are inoperable and recurrent, let alone for multicentric GCTB. This study reports a novel case of multicentric GCTB treated with a promising antiangiogenic drug, apatinib, a small-molecule tyrosine kinase inhibitor. The efficacy of apatinib in the treatment of GCTB has not been reported previously.