Open AccessLRFN2 gene variant rs2494938 provides susceptibility to esophageal cancer in the population of Jammu and Kashmir
Author(s) -
Ruchi Shah,
Varun Sharma,
Hemender Singh,
Indu Sharma,
G. A. Bhat,
Idrees Ayoub Shah,
Beenish Iqbal,
Rumaisa Rafiq,
Najma Nissa,
Mansha Muzaffar,
Malik Tariq Rasool,
Ghulam Nabi Lone,
Sandeep Kaul,
Mohd Maqbool Lone,
Ekta Rai,
Nazir Ahmed Dar,
Swarkar Sharma
Publication year - 2020
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/jcrt.jcrt_613_19
Subject(s) - esophageal cancer , odds ratio , genotype , allele , confidence interval , medicine , incidence (geometry) , population , genetics , oncology , biology , gastroenterology , cancer , gene , environmental health , physics , optics
Leucine-rich repeat and fibronectin type 2 gene (LRFN2) variant rs2494938 has recently been found associated with esophageal cancer in a genome-wide association study in an Asian population. However, this association has not been replicated in any Indian population despite high incidence of the disease.