LRFN2 gene variant rs2494938 provides susceptibility to esophageal cancer in the population of Jammu and Kashmir
Author(s) -
NazirAhmed Dar,
Swarkar Sharma,
Ruchi Shah,
Varun Sharma,
Hemender Singh,
Indu Sharma,
GulzarAhmed Bhat,
IdreesAyoub Shah,
Beenish Iqbal,
R Rafiq,
Najma Nissa,
Mansha Muzaffar,
MalikTariq Rasool,
Mohd Maqbool Lone,
Sandeep Kaul,
MohdMaqbool Lone,
Ekta Rai
Publication year - 2020
Publication title -
journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 1998-4138
pISSN - 0973-1482
DOI - 10.4103/jcrt.jcrt_613_19
Subject(s) - esophageal cancer , odds ratio , genotype , allele , confidence interval , medicine , incidence (geometry) , population , genetics , oncology , biology , gastroenterology , cancer , gene , environmental health , physics , optics
Leucine-rich repeat and fibronectin type 2 gene (LRFN2) variant rs2494938 has recently been found associated with esophageal cancer in a genome-wide association study in an Asian population. However, this association has not been replicated in any Indian population despite high incidence of the disease.
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