Open AccessComparison of safety and efficacy of pregabalin versus gabapentin for the treatment of uremic pruritus in patients with chronic kidney disease on maintenance haemodialysis
Author(s) -
Ashima Ravindran,
Rajesh Peringanazhi Kunnath,
Anjali Sunny,
Binoo Vimal
Publication year - 2020
Publication title -
indian journal of palliative care/indian journal of palliative care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 26
eISSN - 1998-3735
pISSN - 0973-1075
DOI - 10.4103/ijpc.ijpc_212_19
Subject(s) - gabapentin , medicine , pregabalin , visual analogue scale , itching , kidney disease , hemodialysis , anesthesia , surgery , alternative medicine , pathology
Uremic pruritus (UP) affects many patients suffering from chronic kidney disease (CKD) and has a negative impact on the quality of life. The severity of UP ranges from sporadic discomfort to complete restlessness during both day and night time. It has become increasingly evident that central transmission and sensitization processes similar to those observed in chronic pain are important mechanisms of pruritus.