Open AccessPrimary ocular presentation of tuberous sclerosis – A case report
Author(s) -
Nancy Magdalene Rajasekaran,
Saban Horo,
Thomas Kuri̇akose
Publication year - 2019
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_925_18
Subject(s) - medicine , tuberous sclerosis , fundus (uterus) , retinal , ophthalmology , lesion , fluorescein angiography , retina , coats' disease , angiofibroma , presentation (obstetrics) , radiology , pathology , physics , optics
A 25-year-old man presented with decreased vision in the left eye with hypopigmented elevated subretinal lesion over the optic disk with abnormal vasculature, subretinal and retinal hemorrhages, and fluid in the macula. An area of high spike over the disk with corresponding orbital shadowing was seen on B scan ultrasonography. Fundus fluorescein angiography revealed abnormal vasculature. Systemic examination revealed facial angiofibroma, ashleaf spot, and dental pits with multiple cortical tubers on CT brain. Intravitreal injection of bevacizumab led to visual and tomographic improvement. Abnormal retinal vascularization and exudation in young individuals may be a presenting feature in tuberous sclerosis.