Open AccessManagement of multi drug resistant endogenous Klebsiella pneumoniae endophthalmitis with intravitreal and systemic colistin
Author(s) -
Mohit Dogra,
Mansi Sharma,
Deeksha Katoch,
Mangat R Dogra
Publication year - 2018
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_809_17
Subject(s) - colistin , medicine , klebsiella pneumoniae , endophthalmitis , antibiotics , visual acuity , ophthalmology , surgery , microbiology and biotechnology , biochemistry , chemistry , escherichia coli , biology , gene
We report a case of a 35-year-old male with a pancreatic pseudocyst, who developed bilateral endogenous endophthalmitis, 4 days after surgical drainage of the pseudocyst. Bacterial cultures of the pancreatic drain fluid and the vitreous tap showed the growth of Klebsiella pneumoniae. The cultured organism was resistant to all the tested antibiotics except colistin. Intravenous colistin was instituted and three injections of intravitreal colistin were given in the left eye of the patient. Complete resolution of infection was seen and visual acuity of 6/6 was regained in both eyes, which was maintained at 4-month follow-up.