
In vivo confocal microscopy and anterior segment optical coherence tomography follow-up of cysteamine treatment in corneal cystinosis
Author(s) -
Hüseyin Baran Özdemir,
Mehmet Cüneyt Özmen,
Zeynep Aktaş,
Murat Hasanreisoğlu
Publication year - 2019
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_736_18
Subject(s) - cystinosis , medicine , photophobia , cysteamine , optical coherence tomography , confocal microscopy , ophthalmology , confocal , in vivo , pathology , optics , cystine , nuclear magnetic resonance , physics , microbiology and biotechnology , cysteine , biology , enzyme
A 36-year-old female presented initially with photophobia and visual deterioration. After examination and laboratory tests, patient was diagnosed with cystinosis. Cysteamine drops 4 × 1 drops/day was given as treatment for 1 year. During follow-up, in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) was performed. Photophobia was relieved and IVCM obtained the decrease in size and density of corneal crystals 1 year after. Depth of corneal crystals did not change but crystal density score reduced with cysteamine treatment.