Open AccessInterleukins and cytokine biomarkers in uveitis
Author(s) -
S. Balamurugan,
Dipankar Das,
Murat Hasanreisoğlu,
Brian C. Toy,
Mashal Akhter,
V K Anuradha,
Eliza Anthony,
Bharat Gurnani,
Kirandeep Kaur
Publication year - 2020
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_564_20
Subject(s) - uveitis , medicine , immune privilege , immunology , cytokine , interleukin , pathogenesis , immune system , privilege (computing) , computer security , computer science
Interleukins and cytokines are involved in the pathogenesis of uveitis of heterogeneous origin. Understanding the basics of the ocular immune privilege is a fulcrum to discern their specific role in diverse uveitis to potentially translate as therapeutic targets. This review attempts to cover these elements in uveitis of infectious, noninfectious and masquerade origin. Insights of the molecular targets in novel therapy along with the vision of future research are intriguing.