Open AccessSuccessful treatment of allergic conjunctival granuloma by topical tacrolimus: A clinicopathologic case report
Author(s) -
Ali Foroutan,
Abdolhossein Ghafourian,
Abbas Habibi,
Pooria Foroutan,
Maryam Ashrafkhorasani,
Sayyed Amirpooya Alemzadeh
Publication year - 2018
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_490_16
Subject(s) - medicine , tacrolimus , photophobia , itching , asymptomatic , dermatology , red eye , conjunctiva , eye drop , granuloma , surgery , ophthalmology , pathology , transplantation
Allergic conjunctival granuloma is a rare cause of conjunctival ocular lesions. The aim of this case report was to present a successful treatment of an allergic conjunctival granuloma with topical tacrolimus eye drops. A 20-year-old female presented with bilateral multiple yellow nodules of the bulbar conjunctival epithelium and conjunctival injection. The patient had tearing, photophobia, itching, foreign body sensation, and red eye. The patient's signs and symptoms progressed despite the use of topical steroids. The patient was treated by application of tacrolimus eye drop (0.005%) in her right eye every 6 h while the left eye was put on placebo. Her signs and symptoms were recorded at each visit. After 3 weeks' therapy with topical tacrolimus eye drop, the patient became asymptomatic in her right eye and conjunctival granulomas fully resolved. Topical tacrolimus seems to be an effective therapeutic option for the treatment of allergic conjunctival granulomas.