Open AccessTopiramate-induced acute angle closure with severe panuveitis: A challenging case report
Author(s) -
Padmamalini Mahendradas,
Snehanka G Parab,
Rajesh Sasikumar,
Ankush Kawali,
Bhujang Shetty
Publication year - 2018
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1192_17
Subject(s) - medicine , photophobia , ophthalmology , topiramate , discontinuation , visual acuity , glaucoma , migraine , anterior chamber angle , surgery , anesthesia , psychiatry , epilepsy
A 36-year-old female presented with the complaints of pain, photophobia, redness, and sudden diminution of vision in both the eyes following topiramate for migraine treatment. On examination, there was panuveitis with angle-closure glaucoma in both the eyes with fibrinous exudate with pigments in the anterior chamber of the left eye. B scan revealed increased choroidal thickness in both the eyes. Serial anterior segment optical coherence tomography scans were done in the left eye to demonstrate the gradual resolution of the fibrin material from the anterior chamber. There was complete resolution of inflammation in both eyes following discontinuation of topiramate and treatment with systemic and topical steroids. There was an improvement in visual acuity in the left eye following complicated cataract surgery.