Open AccessExpression of p53 and Ki-67 proteins in patients with increasing severity and duration of pterygium
Author(s) -
Mood Mahesh,
Sanjeev Mittal,
Sanjeev Kishore,
Anupam Singh,
Neeti Gupta,
Rimpi Rana
Publication year - 2021
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1034_20
Subject(s) - pterygium , medicine , immunohistochemistry , ki 67 , cornea , gastroenterology , pathology , ophthalmology
Pterygium is a triangular fibrovascular subepithelial ingrowth of degenerative bulbar conjunctival tissue over the cornea. It is now considered to be a result of uncontrolled cellular proliferation as overexpression of p53 protein and Ki-67 nuclear protein was found in the epithelium. This study was done to find the expression of p53 and Ki-67 with the severity and duration of the pterygium to explain the etiopathogenesis.