Open AccessComparative analysis between urinary calprotectin and serum creatinine for early detection of intrinsic acute kidney injury
Author(s) -
Marjan Vakili,
Daryoush Fahimi,
Seyed-Taher Esfahani,
Meysam Sharifzadeh,
Mastaneh Moghtaderi
Publication year - 2021
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_83_20
Subject(s) - medicine , creatinine , calprotectin , acute kidney injury , urinary system , biomarker , receiver operating characteristic , urine , gastroenterology , kidney disease , renal function , urology , disease , inflammatory bowel disease , biochemistry , chemistry
Acute kidney injury (AKI) is a common and important clinical condition that may lead to chronic kidney disease if it is not diagnosed and treated in its early stages. Urinary calprotectin is a valuable recognized biomarker that can be used to differentiate prerenal and intrinsic AKI. However, till date only a few reports on urine calprotectin measurement in early diagnosis of intrinsic AKI are available. In this study, we compared the sensitivity and specificity of urinary calprotectin with those of serum creatinine in detecting early intrinsic AKI.