
Effectiveness of a low dose prednisolone regimen for treatment of relapses in children with steroid sensitive nephrotic syndrome
Author(s) -
Mukta Mantan,
Aparajita Kansal,
Swarnim Swarnim
Publication year - 2022
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_463_21
Subject(s) - medicine , prednisolone , nephrotic syndrome , regimen , pediatrics , randomized controlled trial , gastroenterology , minimal change disease , surgery , focal segmental glomerulosclerosis , glomerulonephritis , kidney
There may be a role of reducing the total steroid doses for the treatment of relapses of nephrotic syndrome in children with milder and more stable disease. The primary objective of this study was to compare the effectiveness of a low-dose prednisolone regimen with standard therapy for the treatment of relapses in steroid-sensitive nephrotic syndrome (SSNS) at the end of treatment, the secondary objectives being time to remission and sustained remission after 3 months.