Open AccessThe Utility of Assessing CD68+ Glomerular Macrophages in Assessing Endocapillary Hypercellularity in IgA Nephropathy
Author(s) -
Neha Agrawal,
Swarnalata Gowrishankar
Publication year - 2021
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_380_19
Subject(s) - cd68 , biopsy , glomerulonephritis , renal biopsy , medicine , pathology , nephropathy , receiver operating characteristic , urology , kidney , immunohistochemistry , endocrinology , diabetes mellitus
IgA nephropathy (IgAN) is the most common form of glomerulonephritis across the world. Oxford classification defines criteria and effects of endocapillary hypercellularity on E score but the reproducibility of the same is debatable. Hence, there is a need for an objective marker that could establish a gold standard in assessing endocapillary hypercellularity.