Open AccessA study of association of urinary nephrin with albuminuria in patients with diabetic nephropathy
Author(s) -
Kishore Kondapi,
N Lakshmana Kumar,
Swathi Moorthy,
Santhi Silambanan
Publication year - 2021
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_305_19
Subject(s) - nephrin , medicine , albuminuria , diabetic nephropathy , urology , diabetes mellitus , urinary system , excretion , endocrinology , podocyte , gastroenterology , proteinuria , kidney
Diabetes mellitus and its complications are associated with high mortality and morbidity. Early detection is mandatory to improve quality of life years in patients with diabetic nephropathy. Hyperglycaemia disrupts podocytes, both structurally and functionally, leading to excretion of nephrin which is present in the glomerular filtration barrier. This study was undertaken to find out whether urinary nephrin is a better indicator of podocyte injury than albuminuria in patients with diabetic nephropathy.