Open AccessAn unusual association of renal cell carcinoma and renal malakoplakia with focal segmental glomerulosclerosis in an elderly patient
Author(s) -
Madhusudan Vijayan,
Priyanka Koshy,
R. Parthasarathy,
Milly Mathew,
Georgi Abraham
Publication year - 2018
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_289_17
Subject(s) - medicine , malakoplakia , focal segmental glomerulosclerosis , renal biopsy , nephrotic syndrome , malignancy , pathology , glomerulonephritis , concomitant , renal cell carcinoma , eosinophilic , biopsy , kidney
The association of malignancy and glomerulonephritis may be missed, especially in elderly patients. Here, we report a case of eosinophilic variant of renal cell carcinoma and renal parenchymal malakoplakia discovered on renal biopsy in a patient with steroid-dependent nephrotic syndrome. The presence of malakoplakia in our biopsy was probably due to systemic steroid therapy for glomerulonephritis, presence of concomitant asymptomatic urinary tract infection, and/or history of diabetes mellitus. The patient had remission of proteinuria following laparoscopic removal of the tumor, indicating probable remission of glomerulonephritis.