Open AccessRenal microvascular ischemia secondary to nonsteroidal anti-inflammatory drugs
Author(s) -
Sagar Kulkarni,
Vipul Chakurkar,
Valentine Lobo
Publication year - 2021
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_211_20
Subject(s) - medicine , nonsteroidal , ischemia , flank pain , lesion , vasculitis , renal ischemia , renal function , kidney , cardiology , surgery , anesthesia , disease , reperfusion injury
Nonsteroidal anti-inflammatory drugs (NSAIDs), widely prescribed for pain, can affect kidneys in various ways. We present a case of a 37-year-old woman with multiple NSAIDs intake over a short period for dysmenorrhea followed by the development of new-onset bilateral flank pain. Computed tomography revealed bilateral multiple renal infarcts. Renal function was normal. Investigations showed no cardiac or renal artery lesion and vasculitis work-up was negative. She was treated conservatively and further NSAID intake was avoided. Follow-up scan showed complete restoration of the blood flow in previously affected areas. Thus, microvascular ischemia secondary to NSAIDs was thought to be responsible.