Open AccessA rare case of APRT deficiency with end-stage renal failure and successful renal transplant
Author(s) -
Manish R. Sharma,
Swarnalata Gowrishankar,
Tarun Jeloka
Publication year - 2021
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_202_19
Subject(s) - medicine , uric acid , kidney , kidney transplantation , kidney disease , nephropathy , urology , transplantation , end stage renal failure , end stage renal disease , kidney stones , disease , hemodialysis , endocrinology , diabetes mellitus
Renal calculus disease is a common cause of renal injury. However, crystal nephropathy (uric acid, oxalate, and dihydroxyadenine) can present as chronic kidney disease without any evidence of renal stones. If left undiagnosed, there is a potential chance of recurrence in the allograft leading to graft failure after transplantation. Pretransplant identification and management can avoid such complications. Here, we describe a case of APRT deficiency leading to crystal nephropathy and end-stage renal failure in a patient who underwent a successful kidney transplant.