Open AccessLymphomatous interstitial nephritis coexistent with paraneoplastic crescentic membranoproliferative glomerulonephritis in a case of mantle cell lymphoma
Author(s) -
Praveen Kumar Etta,
M V Rao,
Sujeet Reddy,
Swarnalata Gowrishankar,
Neha Agarwal
Publication year - 2020
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_160_19
Subject(s) - medicine , membranoproliferative glomerulonephritis , interstitial nephritis , mantle cell lymphoma , pathology , rituximab , lymphoma , nephritis , chop , lymphoproliferative disorders , glomerulonephritis , kidney
Mantle cell lymphoma (MCL) is a rare aggressive lymphoproliferative disorders (LPD) of B-cell lymphoma, which usually presents in advanced stages at initial diagnosis. Renal involvement in MCL is very rare, especially the combined presence of both glomerular and interstitial disease. We report on a patient with lymphomatous interstitial nephritis (LIN) coexistent with paraneoplastic crescentic membranoproliferative glomerulonephritis (MPGN), subsequently diagnosed to have disseminated MCL with bone marrow and lymph nodal infiltration. He was treated with rituximab-based chemotherapy and went into complete renal remission at 6-months of follow up.