Open AccessIn vitro comparison of the cytotoxic effects of statins on U266 myeloma cell line
Author(s) -
Hatice Terzi,
Ahmet Altun,
Mehmet Şencan
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_672_18
Subject(s) - bortezomib , simvastatin , atorvastatin , lovastatin , pharmacology , multiple myeloma , statin , cytotoxicity , cell culture , cell growth , chemistry , medicine , in vitro , immunology , biology , cholesterol , biochemistry , genetics
Statins are one of the most widely used drugs and have antilipidemic effects as well as antioxidant, anti-inflammatory, anti-angiogenic and anti-tumorigenic effects. It has been shown that the synergistic combinations of statins which can provide better clinical benefit in the treatment of cancer and if administered with other anticancer agents, may be an alternative treatment modality. The aim of this study was to assess the efficacy of administrating statin in multiple myeloma (MM) cell line on cell proliferation.