Open AccessClinical significance of galectin-3 expression in malformed hepatic venous tissue
Author(s) -
Jie Qiao,
Yongwei Chen,
Changxian Dong,
Jin Li
Publication year - 2018
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_500_17
Subject(s) - venous malformation , pathological , pathology , medicine , immunohistochemistry , vein , in situ hybridization , clinical significance , galectin 3 , biology , messenger rna , surgery , biochemistry , gene
Hepatic venous malformation gradually develops over time and exhibits the malignant biological behaviours of being locally invasive, causing morphological and functional damage to local tissue, and may even cause systemic coagulopathy. Studies show that galectin-3(Gal-3) expression is closely associated with local invasion of malignant tumours. In this study an attempt was made to assess the clinical significance of Gal-3 in local invasion during hepatic venous malformation in patients.