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The frequently encountered co-morbidity of alcohol dependence (AD) with nicotine dependence (ND) increases the risk for various diseases. Ankyrin repeats and kinase domain containing 1 (ANKK1) gene polymorphism is reported to be associated with both ND and AD. This study was undertaken to investigate the possible association of alcohol and tobacco use variables with ANKK1 polymorphism in co-morbid alcohol- and nicotine-dependent treatment seekers visiting a tertiary care centre in north India.

the indian journal of medical research

Association of ankyrin repeats &amp; kinase domain containing 1 (ANKK1) gene polymorphism with co-morbid alcohol &amp; nicotine dependence: A pilot study from a tertiary care treatment centre in north India