Open AccessComparison of the immunogenicity & protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates
Author(s) -
Labanya Mukhopadhyay,
Pragya D. Yadav,
Nivedita Gupta,
Sreelekshmy Mohandas,
Deepak Y. Patil,
Anita Shete-Aich,
Samiran Panda,
Balram Bhargava
Publication year - 2021
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_4431_20
Subject(s) - immunogenicity , medicine , clinical trial , pandemic , placebo , immunology , covid-19 , vaccine efficacy , vaccine trial , immune system , virology , vaccination , neutralizing antibody , disease , infectious disease (medical specialty) , pathology , alternative medicine
The COVID-19 pandemic has emerged as a global public health crisis and research groups worldwide are engaged in developing vaccine candidates to curb its transmission, with a few vaccines having progressed to advanced stages of clinical trials. The aim of this systematic review was to compare immunogenicity and protective efficacy of various SARS-CoV-2 vaccine candidates tested in non-human primate (NHP) models.