Open AccessClinicopathological study of annexin A5 & apelin in pre-eclamptic placentae with emphasis on foetal outcome
Author(s) -
Senjuti Dasgupta,
Priyanka Maity,
Uma Banerjee,
Partha Mukhopadhyay,
Saswata Saha,
Biplab Das
Publication year - 2021
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_433_21
Subject(s) - apelin , preeclampsia , placenta , medicine , prospective cohort study , obstetrics , pregnancy , gestational age , annexin a5 , endocrinology , fetus , pathology , biology , annexin , staining , receptor , genetics
Pre-eclampsia has remained an elusive disease with serious impacts on both maternal and foetal health. Two novel markers, annexin A5 (ANXA5) and apelin are currently of considerable interest. The present study aimed to determine the placental expression of ANXA5 and apelin in pre-eclamptic placentae and also to elucidate if there is any correlation between the expression of these markers and the clinical features of both, mother and neonate. The comparison between gross and histopathological features of pre-eclamptic placentae and controls was another objective.