Open AccessIndian Council of Medical Research consensus document on hepatocellular carcinoma
Author(s) -
Bhawna Sirohi,
Shailesh V. Shrikhande,
Vinay Gaikwad,
Amol Patel,
Shraddha Patkar,
Mahesh Goel,
Munita Bal,
Atul Sharma,
R.K. Shrimali,
Vikram Bhatia,
Suyash Kulkarni,
Deep Narayan Srivastava,
Tanvir Kaur,
Rupinder Singh Dhaliwal,
Goura Kishor Rath
Publication year - 2020
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_404_20
Subject(s) - medicine , hepatocellular carcinoma , curative treatment , metastasis , targeted therapy , general surgery , radiation therapy , disease , cancer , oncology , surgery , intensive care medicine
This document aims to assist oncologists in making clinical decisions encountered while managing their patients with hepatocellular carcinoma (HCC), specific to Indian practice, based on consensus among experts. Most patients are staged by Barcelona Clinic Liver Cancer (BCLC) staging system which comprises patient performance status, Child-Pugh status, number and size of nodules, portal vein invasion and metastasis. Patients should receive multidisciplinary care. Surgical resection and transplant forms the mainstay of curative treatment. Ablative techniques are used for small tumours (<3 cm) in patients who are not candidates for surgical resection (Child B and C). Patients with advanced (HCC should be assessed on an individual basis to determine whether targeted therapy, interventional radiology procedures or best supportive care should be provided. In advanced HCC, immunotherapy, newer targeted therapies and modern radiation therapy have shown promising results. Patients should be offered regular surveillance after completion of curative resection or treatment of advanced disease.