Open AccessAnalysis of beta-lactamases, blaNDM-1phylogeny & plasmid replicons in multidrug-resistant Klebsiella spp. from a tertiary care centre in south India
Author(s) -
N. Nithya,
Remitha Rabindran,
P. R. Jayasree,
Muhammad Faisal,
P. R. Manish Kumar
Publication year - 2017
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_31_16
Subject(s) - plasmid , biology , replicon , microbiology and biotechnology , multiple drug resistance , klebsiella pneumoniae , antibiotic resistance , genetics , klebsiella , gene , drug resistance , antibiotics , escherichia coli
β-lactamases play a predominant role in drug-resistance amongst Enterobacteriaceae. Presence of genes on transferable plasmids encoding these enzymes favours their dissemination across species and genera within and outside geographical boundaries. This study was aimed to understand the presence of β-lactamases and transferable plasmids in clinical isolates of Klebsiella spp. which can contribute to the spread of resistance determinants.