Open AccessCoexistence of metallo-beta-lactamase-encoding genes in Pseudomonas aeruginosa
Author(s) -
Lavanya Mohanam,
Thangam Me
Publication year - 2017
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_29_16
Subject(s) - integron , pseudomonas aeruginosa , imipenem , biology , microbiology and biotechnology , meropenem , carbapenem , beta lactamase , intergenic region , polymerase chain reaction , multiplex polymerase chain reaction , gene , antibiotic resistance , antibiotics , genetics , bacteria , escherichia coli , genome
The emergence and rapid spread of carbapenem resistance mediated by metallo-beta-lactamase (MBL) in Pseudomonas aeruginosa is of major concern due to limited therapeutic options. This study was aimed at detecting the presence of MBL and its association with integrons in imipenem-resistant P. aeruginosa isolates and to determine their genetic relatedness.