Open AccessA non-inferiority randomized controlled clinical trial comparing Unani formulation & psoralen plus ultraviolet A sol in chronic plaque psoriasis
Author(s) -
Neena Khanna,
Tamanzli,
Khalid Mahmud Siddiqui,
Mani Kalaivani,
Rais-ur-Rahman
Publication year - 2018
Publication title -
indian journal of medical research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_249_16
Subject(s) - medicine , randomized controlled trial , psoriasis area and severity index , psoriasis , plaque psoriasis , puva therapy , psoralen , dermatology , surgery , dna , genetics , biology
Though Unani medications have been used for centuries to treat psoriasis, there is paucity of published studies which have systematically evaluated their efficacy and safety. This study was conducted to establish non-inferiority of Unani medications (oral UNIM-401 and topical UNIM-403) vs psoralen plus ultraviolet A (PUVA) sol in treatment of moderate-severe chronic plaque psoriasis (CPP) in achieving psoriasis area severity index (PASI) 75 at 12 wk and to estimate proportion of patients who relapsed in follow up period of 12 weeks, after having achieved PASI 50.