Open AccessTranscriptome & viral growth analysis of SARS-CoV-2-infected Vero CCL-81 cells
Author(s) -
Dimpal A Nyayanit,
Prasad Sarkale,
Shreekant Baradkar,
Savita Patil,
Pragya D. Yadav,
Anita Shete-Aich,
Kaumudi Kalele,
Pranita Gawande,
Triparna Majumdar,
Rajlaxmi Jain,
Gajanan Sapkal
Publication year - 2020
Publication title -
indian journal of medical research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_2257_20
Subject(s) - vero cell , biology , multiplicity of infection , virology , gene , virus , transcriptome , genome , viral replication , coronaviridae , gene expression , microbiology and biotechnology , genetics , covid-19 , medicine , disease , pathology , infectious disease (medical specialty)
The genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), belonging to the family Coronaviridae, encodes for structural, non-structural, and accessory proteins, which are required for replication of the virus. These proteins are encoded by different genes present on the SARS-CoV-2 genome. The expression pattern of these genes in the host cells needs to be assessed. This study was undertaken to understand the transcription pattern of the SARS-CoV-2 genes in the Vero CCL-81 cells during the course of infection.