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Downregulation of apolipoprotein A-IV in plasma & impaired reverse cholesterol transport in individuals with recent acts of deliberate self-harm
Author(s) -
Boby Mathew,
Krishnamachari Srinivasan,
Johnson Pradeep,
Tinku Thomas,
Shakuntala Kandikuppa Murthy,
Amit Kumar Mandal
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1842_17
Subject(s) - cholesterol , apolipoprotein b , endocrinology , medicine , western blot , chemistry , psychology , biochemistry , gene
The major limiting factor in the prevention of suicide is the limited knowledge on molecular insights in individuals at risk. Identification of peripheral protein markers which can classify individuals at high-risk of suicide might aid in early diagnosis and effective medical intervention. The aim of the present study was, therefore, to analyze the differential regulation of plasma proteins in individuals with deliberate self-harm compared to controls.

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