Open AccessDNA damage induced by exposure to pesticides in children of rural areas in Paraguay
Author(s) -
Stela Benítez Leite,
Deidamia Mercedes Franco de Diana,
Jaime Alfredo Segovia Abreu,
Domingo Santiago Ávalos,
Marta Almada Denis,
Cristina Coronel Ovelar,
María José Samaniego Royg,
Boris Alexei Thielmann Arbo,
Ramón Corvalán
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1497_17
Subject(s) - karyorrhexis , dna damage , comet assay , micronucleus test , binucleated cells , micronucleus , pesticide , toxicology , biology , medicine , physiology , chemistry , genetics , apoptosis , toxicity , dna , programmed cell death , ecology
Chronic exposure to pesticides can damage DNA and lead to cancer, diabetes, respiratory diseases and neurodegenerative and neurodevelopment disorders. The objective of this study was to determine the frequency of DNA damage through the comet assay and micronucleus (MN) test in two groups of children, under 10 yr of age living in rural Paraguay and in relation to pesticide exposure.