Open AccessDetection & analysis of inflammatory cytokines in tears of patients with lacrimal duct obstruction
Author(s) -
Dan Wang,
Nan Xiang,
Wei Kun Hu,
Ban Luo,
Xiang Tian Xiao,
Zhao Yin,
Bin Li,
Rong Liu
Publication year - 2021
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1435_19
Subject(s) - medicine , tears , dacryocystitis , chronic dacryocystitis , proinflammatory cytokine , cytokine , lacrimal duct , tumor necrosis factor alpha , nasolacrimal duct obstruction , interleukin , gastroenterology , inflammation , immunology , dacryocystorhinostomy , pathology , surgery
Tear proteomic changes can be a candidate etiopathogenesis of lacrimal duct obstruction diseases (LDODs). Studies on proteomics have focused primarily on nasolacrimal duct obstruction, and some specific inflammatory cytokines such as interferon (IFN)-α2a, interleukin (IL)-8 and IL-10, have not been investigated. In addition, differences in inflammatory cytokines in tears according to the LDOD subtype have not been reported. This study aimed to quantitatively compare inflammatory cytokines in tears from patients with LDOD and investigate tear-cytokine differences among different LDOD subtypes.