Open AccessExpression of innate immune response genes in upper airway samples of SARS-CoV-2 infected patients: A preliminary study
Author(s) -
Madhu Chhanda Mohanty,
Swapnil Yashwant Varose,
Unnati Prashant Sawant,
Mevis Minin Fernandes
Publication year - 2021
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_131_21
Subject(s) - innate immune system , immunology , immune system , biology , virology , covid-19 , sars virus , airway , gene , medicine , genetics , pathology , disease , infectious disease (medical specialty) , surgery
Upper respiratory mucosa is the entryway for SARS-CoV-2, and cells at this site form the first line of resistance against the pathogens. Innate immune response at this point is crucial for managing the replication and early stage symptoms of virus infection. This study was aimed to evaluate the expression of pattern recognition receptors and cytokines in upper airway cells of SARS-CoV-2 infected patients.