
Pharmacogenetic analyses of variations of measures of cardiovascular risk in Alzheimer's dementia
Author(s) -
Fabricio Ferreira de Oliveira,
Juliana Marília Berretta,
Guido Veiga de Almeida,
Sandro Soares de Almeida,
Elizabeth Chen,
Marı́lia de Arruda Cardoso Smith,
Paulo Henrique Ferreira Bertolucci
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1209_17
Subject(s) - blood pressure , medicine , angiotensin converting enzyme , pharmacogenetics , genotype , creatinine , renal function , endocrinology , cardiology , pharmacology , biology , genetics , gene
Neurodegeneration affects blood pressure variations, while renal function and cerebral perfusion are impaired by vascular risk factors. This study was aimed to estimate variations of measures of cardiovascular risk in Alzheimer's dementia by pharmacogenetic analyses of the effects of angiotensin-converting enzyme (ACE) inhibitors and statins.