Open AccessRole of anti-tissue transglutaminase IgA+IgG antibodies in detection of potential celiac disease in patients with type 1 diabetes
Author(s) -
Navchetan Kaur,
Ranjana Walker Minz,
Sanjay Kumar Bhadada,
Biman Saikia,
Devi Dayal,
Shashi Anand,
Nitin Joshi,
Jagdeep Singh,
Babu Ram Thapa,
Rakesh Kochhar,
Kim Vaiphei
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1136_16
Subject(s) - tissue transglutaminase , medicine , type 1 diabetes , antibody , asymptomatic , immunology , autoantibody , coeliac disease , antigen , disease , gliadin , diabetes mellitus , gastroenterology , biology , pathology , gluten , endocrinology , biochemistry , enzyme
: Celiac disease (CD) can exist in various forms in type 1 diabetes (T1D) patients and can remain undetected, leading to severe complications. This study was aimed to evaluate five commercially available anti-tissue transglutaminase (tTG) ELISA kits with distinct formats for the detection of CD and potential CD in T1D patients. Clinical and demographic profiles of the patients with different disease subsets were also studied.