Open AccessRound cell tumors: Classification and immunohistochemistry
Author(s) -
Shweta Sharma,
R Kamala,
Divya Nair,
T Raju Ragavendra,
Swapnil Mhatre,
Robin Sabharwal,
Basanta Kumar Choudhury,
Vivek Rana
Publication year - 2017
Publication title -
indian journal of medical and paediatric oncology (print)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_84_16
Subject(s) - immunohistochemistry , pathology , hepatoblastoma , medicine , desmoplastic small round cell tumor , rhabdomyosarcoma , synovial sarcoma , histopathology , wilms' tumor , differential diagnosis , sarcoma , lymphoma , neuroblastoma , biology , cell culture , genetics
Round cell tumors as the name suggest are comprised round cells with increased nuclear-cytoplasmic ratio. This group of tumor includes entities such as peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, neuroblastoma, hepatoblastoma, Wilms' tumor, and desmoplastic small round cell tumor. These round cells tumors are characterized by typical histological pattern, immunohistochemical, and electron microscopic features that can help in differential diagnosis. The present article describes the classification and explains the histopathology and immunohistochemistry of some important round cell tumors.