Open AccessUtility of cluster of differentiation 5 and cluster of differentiation 117 immunoprofile in distinguishing thymic carcinoma from pulmonary squamous cell carcinoma: A study on 1800 nonsmall cell lung cancer cases
Author(s) -
Vidya Jha,
Preeti Sharma,
Ashish Kumar Mandal
Publication year - 2017
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_148_16
Subject(s) - cd117 , medicine , cd5 , adenocarcinoma , pathology , large cell , carcinoma , immunohistochemistry , small cell carcinoma , lung cancer , not otherwise specified , cancer , lymphoma , cd34 , biology , genetics , stem cell
Mediastinum harbors a mixed bag of neoplastic lesions with varied therapeutic and prognostic implications. Distinguishing pulmonary squamous cell carcinoma from thymic carcinoma is a challenging task owing to rather nonspecific clinicoradiological features and a considerable overlap in histomorphological features. Thus, we evaluated the diagnostic utility of cluster of differentiation 5 (CD5) and CD117 immunohistochemical markers in distinguishing these tumors.