Open AccessAnalytical study on the efficacy of neoadjuvant chemotherapy using a combination of methotrexate, bleomycin, and cisplatin in the management of advanced squamous cell carcinoma of the buccal mucosa
Author(s) -
Santosh Manohar Kumar,
Srabani Biswas,
Shreya Sarkar,
Syam Sundar Mandal,
Jaydip Biswas
Publication year - 2017
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_123_17
Subject(s) - medicine , bleomycin , methotrexate , chemotherapy , buccal administration , toxicity , cisplatin , oncology , context (archaeology) , stage (stratigraphy) , gastroenterology , surgery , pharmacology , paleontology , biology
Cancers of the buccal mucosa (CaBM) predominate in India with late- stage diagnosis and poor survival, necessitating optimal management. Aim: Our study aimed at testing the efficacy of combination neoadjuvant chemotherapy (NACT) using cisplatin (CIS), bleomycin (BL) and methotrexate (MTX) for reducing tumour volume prior to surgery.