Open AccessCinacalcet: A viable therapeutic option for primary hyperparathyroidism in the elderly
Author(s) -
Hussam Abusahmin,
Ashutosh Surya,
Andrew Aldridge,
Onyebuchi Okosieme,
Gautam Das
Publication year - 2018
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_684_17
Subject(s) - cinacalcet , medicine , primary hyperparathyroidism , parathyroidectomy , confidence interval , hyperparathyroidism , prospective cohort study , calcimimetic , cohort , comorbidity , secondary hyperparathyroidism , urology , surgery , calcium , parathyroid hormone
Parathyroidectomy is usually curative in primary hyperparathyroidism (PHPT), but its utility would be limited if patients are elderly who may either refuse surgery or may have advanced frailty and multimorbidity. We evaluated the effectiveness of cinacalcet, an allosteric modulator of calcium-sensing receptor in PHPT in an elderly cohort of patients.