Open AccessParathyroid hormone replacement versus oral calcium and active vitamin D supplementation in hypoparathyroidism: A meta-analysis
Author(s) -
Rajan Palui,
Rashmi Ranjan Das,
Ayan Roy,
Sadishkumar Kamalanathan,
Sitanshu Sekhar Kar,
Jayaprakash Sahoo,
Sandhiya Selvarajan,
Amit Kumar Satapathy
Publication year - 2020
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_579_19
Subject(s) - medicine , hypoparathyroidism , parathyroid hormone , calcium , vitamin d and neurology , endocrinology , placebo , calcium metabolism , adverse effect , calcitriol , bone remodeling , urinary calcium , hormone replacement therapy (female to male) , gastroenterology , alternative medicine , pathology , testosterone (patch)
Chronic hypoparathyroidism is treated conventionally with active vitamin D and high doses of calcium. Recombinant human parathyroid hormone (PTH) replacement is an attractive option for treating patients with hypoparathyroidism since it can replace the physiological action of native PTH. The aim of our study was to perform a comprehensive evaluation of the effects of PTH replacement on calcium homeostasis, bone metabolism, and daily requirement of calcium and active vitamin D.