Open AccessUtility of TSH receptor antibodies in the differential diagnosis of hyperthyroidism in clinical practice
Author(s) -
Mathew John,
Rejitha Jagesh,
Hima Unnikrishnan,
Manju Manoharan,
Nair Jalaja,
Tittu Oommen,
Deepa Gopinath
Publication year - 2022
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_388_21
Subject(s) - medicine , antibody , differential diagnosis , clinical practice , endocrinology , immunology , pathology , family medicine
Graves' disease (GD) is the most common cause of hyperthyroidism in iodine-sufficient areas. It is important to distinguish GD from other causes of hyperthyroidism for optimal management. Thyroid stimulating hormone receptor antibody (TRAb) test is a commonly used test for this purpose. However, the sensitivity for this test in routine clinical practice may be affected by various factors leading to fallacies in diagnosis.