Open AccessPrevalence rates of ADIPOQ polymorphisms in Indian population and a comparison with other populations
Author(s) -
Sandhya Kiran Pemmasani,
Rasika Raman,
Anuradha Acharya
Publication year - 2018
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_294_17
Subject(s) - adiponectin , genotype , allele , population , genetics , genotype frequency , allele frequency , medicine , biology , obesity , gene , insulin resistance , environmental health
The adiponectin gene, ADIPOQ , encodes an adipocytokine, known as adiponectin hormone. This hormone is known to be associated with insulin sensitization, fat metabolism, immunity, and inflammatory response. Polymorphisms in ADIPOQ gene lower the adiponectin levels, increasing the risk for diabetes and cardiovascular diseases.