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In our institution, we have an ongoing newborn thyroid screening (NBS) program since July 2001. In the initial 9 months, we used cord blood thyroid-stimulating hormone (TSH) (CBTSH) cutoff of 20 mIU/L and thereafter the cutoff was increased to 25 mIU/L. Our objective was to evaluate whether a CBTSH cutoff of 25 mIU/L is sensitive and cost-effective in NBS of congenital hypothyroidism (CH).

indian journal of endocrinology and metabolism

Optimizing cord blood thyroid stimulating hormone cutoff for screening of congenital hypothyroidism—experience from screening 164,000 newborns in a tertiary hospital in India