Open AccessPredisposition of angiotensin-converting enzyme deletion/deletion genotype to coronary artery disease with type 2 diabetes mellitus in South India
Author(s) -
Mani Dhivakar,
Rathika Chinniah,
Padma Malini Ravi,
Krishnan Swaminathan,
RA Janarthanan,
Murali Vijayan,
Kamaraj Raju,
K. Balakrishnan
Publication year - 2017
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_215_17
Subject(s) - medicine , coronary artery disease , genotype , genotyping , angiotensin converting enzyme , odds ratio , type 2 diabetes mellitus , diabetes mellitus , allele , endocrinology , genetics , biology , gene , blood pressure
Worldwide, South Asians contribute to a high proportion of coronary artery disease (CAD) burden, mainly attributed to a high prevalence of diabetes. Early identification of such high-risk individuals would enable aggressive disease modification and prevention of complications. Definition of susceptible genotypes early in the course of disease may be one such avenue for reduction in morbidity and mortality from CAD.